Efek Konsumsi Harian Katekin pada Profil Lipid Individu dengan Berat Badan Lebih dan Obesitas: Literature Review

Maida Tertia Anindya

doi:10.59945/jpnm.v3i2.420

Authors

Maida Tertia Anindya Universitas Airlangga

DOI:

https://doi.org/10.59945/jpnm.v3i2.420

Keywords:

obesitas, berat badan lebih, katekin, profil lipid

Abstract

Obesitas merupakan salah satu sindrom metabolik yang dapat menyebabkan berbagai komplikasi metabolik lainnya, termasuk penyakit kardiovaskular. Peningkatan prevalensi obesitas di Indonesia perlu menjadi perhatian khusus untuk segera ditangani. Salah satu penanganan yang dapat dilakukan adalah dengan konsumsi antioksidan seperti katekin. Dalam artikel ini dilakukan telaah dari jurnal yang diterbitkan 10 tahun terakhir untuk melihat efek dari katekin terhadap profil lipid dengan pada individu dengan berat badan lebih dan obesitas. Ditemukan bahwa efek katekin sangat bergantung pada dosis pemberian dan waktu intervensi dalam mempengaruhi komposisi tubuh dan profil lipid.

References

Chatree, S., Sitticharoon, C., Maikaew, P., Pongwattanapakin, K., Keadkraichaiwat, I., Churintaraphan, M., Sripong, C., Sririwichitchai, R., & Tapechum, S. (2021). Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects. Experimental Biology and Medicine, 246(2), 163–176. https://doi.org/10.1177/1535370220962708

Chen, I.-J., Liu, C.-Y., Chiu, J.-P., & Hsu, C.-H. (2016). Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial. Clinical Nutrition, 35(3), 592–599. https://doi.org/10.1016/j.clnu.2015.05.003

Huang, L.-H., Liu, C.-Y., Wang, L.-Y., Huang, C.-J., & Hsu, C.-H. (2018). Effects of green tea extract on overweight and obese women with high levels of low density-lipoprotein-cholesterol (LDL-C): A randomised, double-blind, and cross-over placebo-controlled clinical trial. BMC Complementary and Alternative Medicine, 18(1), 294. https://doi.org/10.1186/s12906-018-2355-x

Kim, H. M., & Kim, J. (2013). The Effects of Green Tea on Obesity and Type 2 Diabetes. Diabetes & Metabolism Journal, 37(3), 173. https://doi.org/10.4093/dmj.2013.37.3.173

Kirch, N., Berk, L., Liegl, Y., Adelsbach, M., Zimmermann, B. F., Stehle, P., Stoffel-Wagner, B., Ludwig, N., Schieber, A., Helfrich, H.-P., & Ellinger, S. (2018). A nutritive dose of pure (–)-epicatechin does not beneficially affect increased cardiometabolic risk factors in overweight-to-obese adults—A randomized, placebo-controlled, double-blind crossover study. The American Journal of Clinical Nutrition, 107(6), 948–956. https://doi.org/10.1093/ajcn/nqy066

Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M.-T., Corrà, U., Cosyns, B., Deaton, C., Graham, I., Hall, M. S., Hobbs, F. D. R., Løchen, M.-L., Löllgen, H., Marques-Vidal, P., Perk, J., Prescott, E., Redon, J., … Verschuren, W. M. M. (2016). European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). European Heart Journal, 37(29), 2315–2381. https://doi.org/10.1093/eurheartj/ehw106

UNICEF. (2019). Analisis Lanskap Kelebihan Berat Badan dan Obesitas di Indonesia. https://www.unicef.org/indonesia/med ia/15581/file/AnalisisLanskapKelebih anBeratBadandanObesitasdiIndonesia.pdf

WHO. (2024). Obesity and Overweight. https://www.who.int/news-room/fact- sheets/detail/obesity-and-overweight

Wolfram, S. (2007). Effects of Green Tea and EGCG on Cardiovascular and Metabolic Health. Journal of the American College of Nutrition, 26(4), 373S-388S. https://doi.org/10.1080/07315724.2007.10719626