Literature Review Potensi Fotokimia Sulforaphane Dalam Pengelolaan Pasien Hiperglikemia

Authors

  • Nema Tirta Nirmala Universitas Airlangga

Keywords:

Sulforaphane, Antioksidan

Abstract

ABSTRACT

Sulforaphane is a phytochemical compound found naturally in cruciferous vegetables such as broccoli, cabbage, and cauliflower. This compound has gained attention due to its potential in the prevention of chronic diseases. Sulforaphane exhibits various bioactive activities, including antioxidant, anti-inflammatory, and detoxifying effects. The mechanism of action of sulforaphane in disease prevention is believed to involve the induction of phase II detoxifying enzymes, modulation of cell signaling pathways, and inhibition of cancer cell growth. This study uses a journal review method based on data collection through inclusion and exclusion criteria obtained from the Google Scholar search engine, including national journals, textbooks, and scientific articles published after 2015.

Keywords : Sulforaphane, Antioksidan

 

References

Axelsson, A. S., Tubbs, E., Mecham, B., Chacko, S., Nenonen, H. A., Tang, Y., ... & Rosengren, A. H. (2017). Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes. Science translational medicine, 9(394), eaah4477.

Baralić, K., Živanović, J., Marić, Đ., Bozic, D., Grahovac, L., Antonijević Miljaković, E., ... & Đukić-Ćosić, D. (2024). Sulforaphane—A Compound with Potential Health Benefits for Disease Prevention and Treatment: Insights from Pharmacological and Toxicological Experimental Studies. Antioxidants, 13(2), 147.

Dian Puspitasari, D. (2018). Pengaruh metode perebusan terhadap uji fitokimia daun mangrove Excoecaria agallocha. Jurnal Penelitian Pendidikan Sosial Humaniora, 3(2), 424-428.

Endarini, L.H. (2016). Farmakognisi dan Fitokimia. Kementerian Keseharan Republik Indonesia: Jakarta Selatan.

Hei, G., Smith, R. C., Li, R., Ou, J., Song, X., Zheng, Y., ... & Wu, R. (2022). Sulforaphane effects on cognition and symptoms in first and early episode schizophrenia: a randomized double-blind trial. Schizophrenia Bulletin Open, 3(1), sgac024.

Houghton, C. A. (2019). Sulforaphane: its “coming of age” as a clinically relevant nutraceutical in the prevention and treatment of chronic disease. Oxid Med Cell Longev. 2019; 2019: 2716870.

Julianto, T. S. (2019). Fitokimia: Tinjauan Metabolit Sekunder dan Skrining Fitokimia.

Kim, M., & Lee, J. Y. (2023). Beneficial effects of sulforaphane on diabetes and its complications via both Nrf2-dependent and independent mechanisms. Food Supplements and Biomaterials for Health, 3(1).

Malaguti, M., Angeloni, C., Garatachea, N., Baldini, M., Leoncini, E., Collado, P. S., ... & Hrelia, S. (2009). Sulforaphane treatment protects skeletal muscle against damage induced by exhaustive exercise in rats. Journal of Applied Physiology, 107(4), 1028-1036.

Maslahah, N., & Nurhayati, H. (2024). Manfaat Kesehatan Beberapa Senyawa Fitokimia. Warta BSIP Perkebunan, 2(3), 22-25.

Meigaria, K. M., Mudianta, I. W., & Martiningsih, N. W. (2016). Skrining fitokimia dan uji aktivitas antioksidan ekstrak aseton daun kelor (Moringa oleifera). Wahana Matematika dan Sains: Jurnal Matematika, Sains, dan Pembelajarannya, 10(2), 1-11.

Nugroho, A. (2017). Teknologi Bahan Alam. Lambung Mangkurat University Press: Banjarmasin.

Ruhee, R. T., & Suzuki, K. (2024). The Immunomodulatory Effects of Sulforaphane in Exercise-Induced Inflammation and Oxidative Stress: A Prospective Nutraceutical. International Journal of Molecular Sciences, 25(3), 1790.

Houghton, C. A. (2019). Sulforaphane: its “coming of age” as a clinically relevant nutraceutical in the prevention and treatment of chronic disease. Oxid Med Cell Longev. 2019; 2019: 2716870.

Widiwurjani, W., Guniarti, G., & Andansari, P. (2019). Status kandungan sulforaphane microgreens tanaman brokoli (Brassica oleracea L.) pada berbagai media tanam dengan pemberian air kelapa sebagai nutrisi. Jurnal Ilmiah Hijau Cendekia, 4(1), 34-38.

Downloads

Published

2025-07-22

How to Cite

Nirmala, N. T. (2025). Literature Review Potensi Fotokimia Sulforaphane Dalam Pengelolaan Pasien Hiperglikemia. JPNM Jurnal Pustaka Nusantara Multidisiplin, 3(2). Retrieved from https://journalpustaka.com/index.php/jpnm/article/view/563